[HTML][HTML] Flaxseed enriched diet-mediated reduction in ovarian cancer severity is correlated to the reduction of prostaglandin E2 in laying hen ovaries

E Eilati, K Hales, Y Zhuge, KA Fricano, R Yu… - … and Essential Fatty …, 2013 - Elsevier
Prevention of ovarian cancer is the best approach for reducing the impact of this deadly
disease. The laying hen is a robust model of spontaneous ovarian cancer that recapitulates
the human disease. Dietary intervention with flaxseed, the richest vegetable source of
omega-3 fatty acids (OM-3FAs) and phytoestrogen lignans, demonstrate the potential for
effective prevention and amelioration of ovarian cancer by targeting inflammatory
prostaglandin pathways. Prostaglandin E 2 (PGE 2) is the most pro-inflammatory ecoisanoid …
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